Links to articles commenting on our recently published discoveries and success.
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back to topRead the whole story on the Faculty of Medicine website.
back to topOur recent Nature Methods paper describing the development and power of the MaMTH technology:
“This technology gives us a new tool to examine membrane proteins in their natural environment of the human cell,” said Igor Stagljar, a professor in the Donnelly Centre for Cellular and Biomolecular Research. “As well, it’s sensitive enough to detect minor changes upon introduction of drugs, so it should prove useful in the development of therapeutics, particularly for cancer and neurological diseases.”back to top
Excerpt:
"ABC transporter proteins act as cellular gatekeepers by retaining nutrients and expelling toxins from the cell. If these proteins are not working properly, it can cause a number of diseases including: cystic fibrosis, age-related macular degeneration, Tangier disease, and Dubin-Johnson syndrome. ABC proteins can also cause cancer cells to reject chemotherapy drugs which makes treatment less effective."
Read the whole article on Crown, the Croatian World Network site.
back to topFrom the article:
Professor Igor Stagljar ... and his team have developed the first road map for an important group of proteins known as ATP-binding cassette (ABC) transporter proteins.
"Our discovery shows how ABC transporter proteins affect cancer and other diseases, and this knowledge can help us develop better, more targeted drugs," said Stagljar. "This is truly momentous."
Read the whole article on the UofT News site.
back to topIgor Stagljar was interviewed for the success cover story article “The Scientist to Watch” that appeared in the September 2012 edition of the Canadian Immigrant magazine. Download the printed article as a PDF or read online on CanadianImmigrant.ca
back to topInterview with Dr. Igor Stagljar for the Madog in Motion Radio
http://madog.ca/madoginmotion/?p=681
http://www.news.utoronto.ca/health-and-medicine/research-promising-for-cystic.html (2008)
http://www.medicalnewstoday.com/articles/67712.php (2007)
About the 2009 Science Signaling paper in the Croatian News (Dec 19, 2010): http://www.hrt.hr/index.php?...
A research highlight regarding the Science Signaling paper in Nature Chemical Biology (2010) PDF
About CCBR (2010) PDF
About Igor in the Croatia Airlines in flight magazine (2009) PDF
About Igor's move to Canada from the Swiss newspaper Beobachter (2005) PDF
About the research in the Stagljar lab from The Scientist (2008) PDF
Article about The Donnelly Centre in the U of T Medicine Bulletin (2010) PDF
From the Canadian Press regarding the discovery in the field of Cystic Fibrosis (2008) PDF
From the Swiis Innovation Promotion Agency (2005) PDF
The experts talk about protein interactions - from Genome Technology (2007) PDF
back to topIgor Stagljar at Hrvatska Uzivo on Dec 8, 2009 http://www.youtube.com/watch?v=-6dILUCAx9g
One day in the Stagljar lab. Filmed by maestro Matt Chuk, a graduate student in the Stagljar lab. Nov-7-2008 http://www.youtube.com/watch?v=Dc9Wl3GcaDk
About Igor Stagljar
http://www.youtube.com/watch?v=moA40SH-czA