For a complete program, click here.

Symposium Organizer, John Glover, welcomes participants and describes the goals
of the CIHR Strategic Training Program in Protein Folding

 

Breakfast and coffee breaks each day offered a great opportunity for interactions
between trainees, mentors and guest speakers.

 

A superb lineup of international experts provided an exciting two days filled
with diverse approaches to study protein folding and associated diseases

Benoit Giasson (U. Penn) Genetic and molecular effectors of alpha-synuclein aggregation involved in Parkinson's disease.		Witold Surewicz (Case Western) Prions: the emerging principles of ppropagation and transmissibility barriers.		David Westaway (Toronto) Functional analysis of mammalian prion proteins.		Peter Csermely (Semmelweis, U., Budapest) Molecular chaperones and networks.

 

Walid Houry (Toronto) ClpXP: a protein unfolding and degradation system.		Dan Hebert (U. Mass.) N-linked glycoproteins in glycoprotein maturation and quality control.		Harold Scheraga (Cornell) The two aspects of the protein folding problem.		Lewis Kay (Toronto) Seeing the invisible by solution NMR spectroscopy

 

José Onuchic (UCSD) From the protein folding landscape to atomistic simulations.		Uno Carlsson (Linköping U., Sweden) Biophysical mapping of folding, unfolding and misfolding of carbonic anhydrase with and without chaperones.

 

Uno Carlsson chats with Biochemistry Chair Reinhart Reithmeier after the session.		Hue-Sun Chan catches up with José Onuchic

 

 

A sumptuous lunch put everyone in the mood for posters.

Poster Session

Ronnie Lum describes the Hsp104 disaggregase to Dan Hebert		John Glover looks over Achim Brockmeier's work on the calnexin molecular chaperone.

 

Mikael Borg judges Régis Pomès' reaction to his "as simple as possible" lattice model of protein interactions.		Only the Shadoo knows.... Vivian Ng takes Boris Steipe through her expression of the Shadoo protein

 

Fiona Cunningham describes her delta-helix concept to Shoshana Wodak.		Arash Zarrine-Afsar fields questions from José Onuchic

 

 

The high quality of the work accomplished by the program's trainees was showcased
both in the poster session as well as in oral presentations.

M.Sc. Student Sarah Mansour Investigating the molecular basis for the aggregation and elastomeric properties of elastin.		PDF Dmitry Korzhnev Probing the ensembles of transition and intermediate states of a protein folding reaction by pressure dependent NMR relaxation		M.Sc. Student Usheer Kanjee Function of RavA chaperone and its interaction with lysine decarboxylase: X-ray structure of Ldc1

PDF Tanja Mittag Compactness of disordered Sic1 is important for its switch-like interaction with Cdc4				Ph.D. Student Gamal Rayan Effect of osmolytes on the hydration of myoglobin

 

The Symposium brought together three generations of protein biochemists - the Scheraga legacy.

Vice Dean Research, Peter Lewis (left) and Prof. Walid Houry (right) pose with their Ph.D mentor Harold Scheraga

Guest speakers gather with their hosts to toast the success of the Symposium.