Scenes from the First CIHR Strategic Training Program International Symposium on
Proteins: Structure, Folding and Disease


Medical Sciences Building , University of Toronto
June 3rd and 4th, 2004

For a complete program, click here to download pdf.


Workshop Chair, Charles Deber, welcomes participants and describes the goals
of the CIHR Strategic Training Programs in Membrane Proteins and Protein Folding

 

A superb lineup of renowned scientists and local trainees attracted about
300 participants to the Symposium

 

The Thursday Morning Session Focused on Membrane Proteins - Structure and Diseases

Don Engelman (Yale) led off with the folding and evolution of membrane proteins
 
James Bowie (UCLA) discussed membrane protein structure, energetics and disease

Julie Forman-Kay (Toronto) provided insights into the structures of disordered proteins
 
Mark Sansom (Oxford) described his simulation studies on membrane proteins

 

 
Lunch was a great opportunity for mentors and trainees to discuss science in an informal setting

 

On Thursday Afternoon the program's trainees stole the show
with the exceptional quality of their presentations and research accomplishments

PDF Ahmed El Zoeiby
Structure & Function of an endotoxin-modifying enzyme

 

PhD Student Peter Hwang
Integral membrane protein PagP alternates between two dynamically distinct states

 
PDF Hania Wehbi
NMR investigation of a transmembrane helical hairpin segment from CFTR

PhD Student Sean Reichheld
Mech. of interdomain collaboration in drug-binding activity of tetracycline repressor
 
PhD Student Yulia Tsitrin
Structural aspects of the ClpX chaperone functional cycle
 
PDF Minghua Wang
G-protein coupled metabotropic glutamate receptors as targets for drug design

 



Enjoying a wine and cheese reception for guest speakers, mentors, and trainees

 

Yulia Tsitrin and Monika Niggemann discuss wine and proteins with Charlie Deber
 
Régis Pomès argues the structural dynamics of PagP (or is it a teacup?) with Peter Hwang and Shao-Yang Ku


Trainees and mentors alike took advantage of the reception to meet our guest speakers

 


Enjoying Friday breakfast

 

The Friday Morning Session focused on Protein Folding and Misfolding

Chris Dobson (Cambridge) led off with a discussion of protein misfolding and disease
 
Michael Hecht (Princeton) described protein design from combinatorial libraries

David Williams (Toronto) discussed glycoprotein folding assisted by lectin-chaperones

 

Ulrich Hartl (Max Planck) finished off by describing chaperone-assisted folding in the cytosol

 

 

Speakers relaxing after a day of excellent science
 
Speakers, hosts, and organizers celebrate the success of our inaugural Symposium

 

 

Photos by David Williams. Reinhart Reithmeier, and Joe at Adega

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